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▪ 1.1. Identification and characterizing inhibitors of Wht, AKT and p53 pathways
▪ 1.2. Mechanisms studies and preclinical development of CD443MUT
▪ 1.3. Phase I-II clinical trials of VIREXXA
▪ 1.4. Novel chemically modified oligonucleotides as anti-cancer drugs
▪ 1.5. Cellular Immunotherapy
▪ 1.6. Modulation of miRNA levels in cancer cells
▪ 1.7. Anticancer vaccines based on Plant Virus Coat Protein Virus Like Particles
▪ 2.1. Plexins and semaphorins in cancer diagnostics and therapy
▪ 2.2. Molecular diagnostic analyzes for personalized therapy
▪ 2.3. Blood tests for breast cancer
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▪ Estonian HealthTech Cluster

CCCR is currently running 10 projects in two strategic development orientations:

1st: Development of new generation cancer drugs.
Head of Drug Development: Priit Kogerman, PhD (priit [.] kogerman [@] vtak [.] ee)

1.1. Identification and characterizing inhibitors of Wnt, AKT and p53pathways
1.2. Mechanisms studies and preclinical development of CD443MUT
1.3. Phase I-II clinical trials of VIREXXA
1.4. Novel chemically modified oligonucleotides as anti-cancer drugs
1.5. Cellular Immunotherapy
1.6. Modulation of miRNA levels in cancer cells
1.7. Anticancer vaccines based on Plant Virus Coat Protein (CP) Virus Like Particles (VLPs)

2nd: Development and implementation of new technological platforms for early diagnosis and prognosis of cancer
Head of Diagnostics: Toomas Neuman, PhD (toomas [.] neuman [at] vtak [.] ee)

2.1. Plexins and semaphorins in cancer diagnostics and therapy
2.2. Molecular diagnostic analyzes for personalized therapy
2.3. Blood tests for Breast Cancer